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Reka letak terusan sebagaimana yang dilihat oleh sebuah kapal yang belayar dari hujung Pasifik ke Atlantik adalah seperti yang berikut: <ref>[http://historicals.ncd.noaa.gov/historicals/histmap.asp Laman web NOAA: Peta & Projek Carta Sejarah] – termasuk carta-carta Terusan Panama</ref>
* FromDari thepermulaan beginningsaluran ofmasuk theberboya [[buoy|buoyed]] entrance channel in the Gulfke ofTeluk Panama, shipskapal-kapal travelbelayar 13.2 [[kilometrekilometer]]s (8.2 [[mileBatu (ukuran)|mi batu]]) upmelalui thesaluran channelke topintu-pintu theair Miraflores locks, passingsemasa merentasi underdi thebawah [[BridgeJambatan of the AmericasAmerika]];
* TheSistem two-stagepintu air Miraflores lock systemdua-peringkat, includingtermasuk thetembok approach walltuju, isialah 1.7 kilometreskilometer (1.1 mibatu) longpanjangnya, withdengan akenaikan total lift ofsebanyak 16.5 [[metremeter]]s (54 [[footKaki (unit of lengthukuran)|ftkaki]]) atpada mid-tide[[pasang surut]] tengah;
* The artificial [[Tasik Miraflores Lake]] isbuatan theialah nextperingkat stageberikut, dengan 1.7 kilometreskilometer (1.0 mibatu) longpanjangnya, anddan 16.5 metresmeter (54 ftkaki) abovedi seaatas levelaras laut;
* ThePintu single-stageair Pedro Miguel lock,satu whichperingkat isyang 1.4 kilometreskilometer (0.8 mibatu) long,panjangnya isialah thebahagian lastkenaikan partterakhir, ofdengan thekenaikan ascent with a lift ofsebanyak 9.5 metresmeter (31 ftkaki) up tonaik theke mainaras levelutama of the canalterusan;
* The [[Gaillard Cut|Gaillard (Culebra) Cut]] slices 12.6 kilometres (7.8 mi) through the [[continental divide]] at an altitude of 26 metres (85 ft), and passes under the [[Centennial Bridge, Panama|Centennial Bridge]]
* The [[Chagres River]] (Río Chagres), a natural waterway enhanced by the damming of Lake Gatún, runs west about 8.5 kilometres (5.3 mi), merging into Lake Gatun
* [[Gatun Lake]], an artificial lake formed by the building of the [[Gatun Dam]], carries vessels 24.2 kilometres (15.0 mi) across the isthmus
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