SIDT1

SIDT1
Pengecam
Alias	SIDT1, B830021E24Rik, SID-1, SID1, SID1 transmembrane family member 1
Pengecam-pengecam luaran	OMIM: 606816 MGI: 2443155 HomoloGene: 41189 GeneCards: SIDT1
Kedudukan gen (Manusia)
Kr.	Kromosom 3
Tamat	113,629,575 bp
Corak ekspresi RNA
	Top expressed in
	rektum; ; timus; ; nodus limfa; ; limpa; ; Pundi hempedu; ; dorsolateral prefrontal cortex; ; Brodmann area 9; ; bronchial epithelial cell; ; prefrontal cortex; ; darah;
	Top expressed in
	superior frontal gyrus; ; kelenjar air mata; ; primary motor cortex; ; kelenjar parotid; ; korteks serebelum; ; submandibular gland; ; hippocampus proper; ; cingulate gyrus; ; darah; ; secondary oocyte;
	More reference expression data
	tiada data
Ontologi gen
Fungsi molekul	RNA transmembrane transporter activity; RNA binding; double-stranded RNA binding;
Komponen sel	membran; integral component of membrane; Lisosom; Membran plasma;
Proses biologi	dsRNA transport; RNA transport;
	Sumber:Amigo / QuickGO
Ortolog
	54847
	320007
	ENSG00000072858
	ENSMUSG00000022696
	Q9NXL6
	Q6AXF6
NM_001308350; NM_017699; NM_001322294; NM_001322295; NM_001322296;
	NM_001322297; NM_001322298; NM_001322299; NM_001322300
	NM_001159419; NM_198034
NP_001295279; NP_001309223; NP_001309224; NP_001309225; NP_001309226;
	NP_001309227; NP_001309228; NP_001309229; NP_060169
	NP_001152891; NP_932151
	Wikidata
Papar/Sunting data manusia	Papar/Sunting data mencit

Ahli 1 keluarga transmembran SID1 adalah sejenis protein terdapat di manusia yang dikod oleh gen SIDT1. ^[4]

Fungsi sunting

Protein yang dikodkan oleh gen ini adalah salah satu saluran berpagar dsRNA transmembran dibawah keluarga SID1. Ahli-ahli keluarga ini mengangkut dsRNA ke dalam sel untuk keperluan dalam campur tangan fungsi RNA secara sistemik.

Rujukan sunting

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000072858 - Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: SID1 transmembrane family member 1". Dicapai pada 2017-10-02.

Bacaan lanjutan sunting

Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR (2010). "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score". Mol. Med. 16 (7–8): 247–53. doi:10.2119/molmed.2009.00159. PMC 2896464. PMID 20379614.
Elhassan MO, Christie J, Duxbury MS (2012). "Homo sapiens systemic RNA interference-defective-1 transmembrane family member 1 (SIDT1) protein mediates contact-dependent small RNA transfer and microRNA-21-driven chemoresistance". J. Biol. Chem. 287 (8): 5267–77. doi:10.1074/jbc.M111.318865. PMC 3285307. PMID 22174421.

Rencana genetik ini ialah rencana tunas. Anda boleh membantu Wikipedia dengan mengembangkannya.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000072858 - Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[3] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-4] "Entrez Gene: SID1 transmembrane family member 1". Dicapai pada 2017-10-02.

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