Sindrom keradangan multisistem pada kanak-kanak

Sindrom keradangan multisistem pada kanak-kanak (MIS-C), atau sindrom multisistem keradangan pediatrik (PIMS / PIMS-TS), ialah penyakit sistemik jarang berlaku yang melibatkan demam terus-menerus dan keradangan ekstrem setelah dijangkiti SARS-CoV-2, virus yang menyebabkan COVID-19.

Sindrom keradangan multisistem pediatrik (PMIS/PIMS/PIMS-TS)
Penafian perubatan
Nama lain	Multisystem inflammatory syndrome in children (MIS-C) Multisystem inflammatory syndrome (MIS) in children and adolescents temporally related to COVID-19 Paediatric inflammatory multisystem syndrome (PIMS), temporally associated with SARS-CoV-2 infection (PIMS-TS) Kawa-COVID-19
Imej TEM SARS-CoV-2, koronavirus yang bertanggungjawab terhadap COVID-19: PMIS / MIS-C dikatakan telah diakibatkan oleh tindak balas biologi luar biasa jangkitan terhadap kanak-kanak
Pengkhususan	Pediatrik
Gejala	Fever, kesakitan abdomen, diarea/muntah, tekanan darah rendah, bekalan darah tidak mencukupi (kejutan), mata merah jambu, "lidah strawberi", ruam, limfus noda besar, tangan/kaki nengkak, gangguan neurologi, among others
Kerumitan	Cardiac dysfunction; coronary artery abnormalities, including aneurysms; acute kidney injury; coagulopathy
Permulaan biasa	typically 2–6 weeks after COVID-19 exposure
Punca	Koronavirus sindrom pernafasan akut teruk 2 (SARS-CoV-2)
Kaedah diagnosis	Clinical evaluation by specialists
Diagnosis pembezaan	Alternative infectious/non-infectious causes, penyakit Kawasaki
Rawatan	Intravenous immunoglobulin (IVIG); kortikosteroid; oxygen, supportive care
Prognosis	Response to treatment, generally good; long-term prognosis, unclear
Kekerapan	Rare
Kematian	<2% of reported cases
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Pautan luar

• Fact sheet for parents released by New York City's Health Department
• Information for parents provided by the Children's Hospital Los Angeles
• Information for paediatric health care providers in the U.S.A. (from the CDC)