Penyakit anemia: Perbezaan antara semakan

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Nik aziz (bincang | sumb.)
Nik aziz (bincang | sumb.)
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===Anemia makrosit===
* Punca utama anemia makrostik anemiamakrositik adalah kekurangan samaadasama ada [[vitamin B12]] atau [[asid folik]] (atau kedua-duanya) akibat samaadasama ada kurang pengambilan atau penyerapan kurang.<ref>[http://www.yahoo.com/s/1037547 Vitamin B12 can prevent major birth defects]</ref> Anemia pernikiouspernisious (''anemia pernisius / anemia pernisius'') adalah keadaan [[autoimmune]] (autoimun) di mana badakbadan kekurangan faktor intrisik, diperlukan bagi menyerap vitamin B12 daripada makanan.
* [[Alcoholism]] (alkoholisme) can cause macrocytic anemia.
* [[Hemolytic anemia]] is a separate constellation of symptoms (also featuring [[jaundice]] (jaundis) and elevated [[lactate dehydrogenase|LDH]] (laktat dehidrogenase) levels) with numerous potential causes. It can be [[autoimmune]], [[genetic disorder|hereditary]] (gangguancelaru genetik) and mechanical (mekanikal)(e.g. [[heart surgery]])(bedah jantung).
 
The treatment for vitamin B12-deficient macrocytic anemia was first devised by [[William Parry Murphy|William P. Murphy]] who bled dogs to make them anemic and then fed them various substances to see what (if anything) would make them healthy again. He discovered that ingesting large amounts of liver seemed to cure the disease. [[George Richards Minot|George R. Minot]] and [[George Hoyt Whipple|George H. Whipple]] then set about to chemically isolate the curative substance and ultimately were able to isolate the [[vitamin B12]] from the liver. For this, all three shared the [[1934]] [[Nobel Prize in Physiology or Medicine|Nobel Prize in Medicine]].