CXCL7

CXCL7
Struktur sedia ada
PDB	Pencarian UniProt manusia: PDBe RCSB
Senarai kod PDB
	1TVX, 1F9P, 1NAP
Pengecam
Alias	PPBP, B-TG1, Beta-TG, CTAP-III, CTAP3, CTAPIII, CXCL7, LA-PF4, LDGF, MDGF, NAP-2, PBP, SCYB7, TC1, TC2, TGB, TGB1, THBGB, THBGB1, pro-platelet basic protein
Pengecam-pengecam luaran	OMIM: 121010 HomoloGene: 136759 GeneCards: PPBP
Kedudukan gen (Manusia)
Kr.	Kromosom 4
Tamat	73,988,190 bp
Corak ekspresi RNA
	Top expressed in
	monocyte; ; spongy bone; ; darah; ; bone marrow cells; ; periodontal fiber; ; limpa; ; right lung; ; buah lengan; ; upper lobe of left lung; ; lower lobe of lung;
	tiada data
	More reference expression data
	Rujukan lanjutan untuk data ekspresi
Ontologi gen
Fungsi molekul	growth factor activity; cytokine activity; glucose transmembrane transporter activity; CXCR chemokine receptor binding; chemokine activity; Pengikatan protein plasma;
Komponen sel	platelet alpha granule lumen; extracellular region; Ekstrasel; tertiary granule lumen; platelet alpha granule;
Proses biologi	response to lipopolysaccharide; regulation of cell population proliferation; chemotaxis; positive regulation of cell division; platelet degranulation; defense response to bacterium; inflammatory response; immune response; chemokine-mediated signaling pathway; defense response; positive regulation of neutrophil chemotaxis; antimicrobial humoral immune response mediated by antimicrobial peptide; regulation of signaling receptor activity; neutrophil degranulation; cell chemotaxis; G protein-coupled receptor signaling pathway; glucose transmembrane transport; neutrophil chemotaxis; leukocyte chemotaxis; cellular response to lipopolysaccharide;
	Sumber:Amigo / QuickGO
Ortolog
	5473
	tiadadata
	ENSG00000163736
	tiadadata
	P02775
	tiada data
	NM_002704
	tiada data
	NP_002695
	tiada data
	Wikidata
Papar/Sunting data manusia

Ligan kemokin (motif C-X-C) 7 (CXCL7) ialah gen manusia.^[4] Protein terkod itu ialah sitokina kecil yang tergolong dalam keluarga kemokina CXC dan merupakan salah satu isobentuk protein Beta-Tromboglobulin atau protein asas pro-platelet (PPBP).^[5]

CXCL7 ialah protein yang dibebaskan pada jumlah yang besar oleh platelet, selepas pengaktifannya.^[6] Ia merangsangkan berbagai-bagai proses, termasuk: ^[7]^[8]

Rujukan sunting

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000163736 - Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)".
^ Hristov M, Zernecke A, Bidzhekov K; dll. (2007). "Importance of CXC chemokine receptor 2 in the homing of human peripheral blood endothelial progenitor cells to sites of arterial injury". Circ. Res. 100 (4): 590–7. doi:10.1161/01.RES.0000259043.42571.68. PMID 17272812. Unknown parameter |month= ignored (bantuan); Explicit use of et al. in: |author= (bantuan)CS1 maint: multiple names: authors list (link)
^ Majumdar S, Gonder D, Koutsis B, Poncz M (1991). "Characterization of the human beta-thromboglobulin gene. Comparison with the gene for platelet factor 4". J Biol Chem. 266 (9): 5785–9. PMID 1826003.CS1 maint: multiple names: authors list (link)
^ Castor C, Miller J, Walz D (1983). "Structural and biological characteristics of connective tissue activating peptide (CTAP-III), a major human platelet-derived growth factor". Proc Natl Acad Sci USA. 80 (3): 765–9. doi:10.1073/pnas.80.3.765. PMID 6572368.CS1 maint: multiple names: authors list (link)
^ Castor C, Furlong A, Carter-Su C (1985). "Connective tissue activation: stimulation of glucose transport by connective tissue activating peptide III". Biochemistry. 24 (7): 1762–7. doi:10.1021/bi00328a029. PMID 4005226.CS1 maint: multiple names: authors list (link)

Rencana genetik ini ialah rencana tunas. Anda boleh membantu Wikipedia dengan mengembangkannya.

Templat:Pemodulat reseptor kemokin

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000163736 - Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[3] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-4] "Entrez Gene: PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)".

[5] Hristov M, Zernecke A, Bidzhekov K; dll. (2007). "Importance of CXC chemokine receptor 2 in the homing of human peripheral blood endothelial progenitor cells to sites of arterial injury". Circ. Res. 100 (4): 590–7. doi:10.1161/01.RES.0000259043.42571.68. PMID 17272812. Unknown parameter |month= ignored (bantuan); Explicit use of et al. in: |author= (bantuan)CS1 maint: multiple names: authors list (link)

[6] Majumdar S, Gonder D, Koutsis B, Poncz M (1991). "Characterization of the human beta-thromboglobulin gene. Comparison with the gene for platelet factor 4". J Biol Chem. 266 (9): 5785–9. PMID 1826003.CS1 maint: multiple names: authors list (link)

[7] Castor C, Miller J, Walz D (1983). "Structural and biological characteristics of connective tissue activating peptide (CTAP-III), a major human platelet-derived growth factor". Proc Natl Acad Sci USA. 80 (3): 765–9. doi:10.1073/pnas.80.3.765. PMID 6572368.CS1 maint: multiple names: authors list (link)

[8] Castor C, Furlong A, Carter-Su C (1985). "Connective tissue activation: stimulation of glucose transport by connective tissue activating peptide III". Biochemistry. 24 (7): 1762–7. doi:10.1021/bi00328a029. PMID 4005226.CS1 maint: multiple names: authors list (link)

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